Position Description

Protein Crystallization Researcher
Location CORPORATE - Seattle
# of openings 1
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Protein Crystallization Researcher



This position will support the research project team with protein structure information. The Protein Crystallization Researcher will be responsible for processing of soluble proteins and GPCRs, and operate the crystallization facility, supporting multiple ongoing discovery programs.



Come join Omeros!

Come join our Discovery Team!



Omeros is a commercial-stage biopharmaceutical company committed to discovering, developing and commercializing small-molecule and protein therapeutics for large-market as well as orphan indications targeting inflammation, complement-mediated diseases and disorders of the central nervous system.

The company’s drug product OMIDRIA® (phenylephrine and ketorolac intraocular solution) 1% / 0.3% is marketed in the U.S. for use during cataract surgery or intraocular lens (IOL) replacement to maintain pupil size by preventing intraoperative miosis (pupil constriction) and to reduce postoperative ocular pain. In the European Union, the European Commission has approved OMIDRIA for use in cataract surgery and other IOL replacement procedures to maintain mydriasis (pupil dilation), prevent miosis (pupil constriction), and to reduce postoperative eye pain.

Omeros has multiple Phase 3 and Phase 2 clinical-stage development programs focused on: complement-associated thrombotic microangiopathies; complement-mediated glomerulonephropathies; Huntington’s disease and cognitive impairment; and addictive and compulsive disorders. In addition, Omeros has a diverse group of preclinical programs and a proprietary G protein-coupled receptor (GPCR) platform through which it controls 54 new GPCR drug targets and corresponding compounds, a number of which are in preclinical development. The company also exclusively possesses a novel antibody-generating platform



What are your job responsibilities?


Your responsibilities in this position will include:


  • Prepare protein crystals for structural analysis


  • Setup, inspect and harvest protein crystals for X-ray diffraction analysis


  • Manage wet lab equipment for new formulation generation, liquid dispensation as well as crystal inspection and handling


  • Operate laboratory robotics for preparing and inspection of crystallization trials


  • Manage and document protein crystallization trials data


  • Present scientific results effectively


  • Attend project meetings


What education and experience do you need?


  • A BS degree with a minimum of 2 years of relevant experience is required


  • Experience with protein crystallization techniques, especially membrane proteins and/or automated liquid handling or imaging systems is a plus.


Knowledge and Skills required:


  • Excellent interpersonal, written and verbal communication skills


Behavioral Competencies Required: 


  • Demonstrated ability to build and maintain positive relationships with management, peers, and subordinates


  • Demonstrated ability to work in a team oriented, highly motivated environment including the ability to foster collaboration


  • Demonstrated ability to present scientific results to project teams and management


  • Time management skills


  • Problem-solving skills


  • Ability to work effectively under high pressure, handling multiple priorities simultaneously


Physical Demands Required: 


  • Intermittent physical activity including bending, reaching, pushing, pulling, or lifting up to 40 lbs.


  • May encounter prolonged periods of sitting or standing 


  • This position requires working around hazardous materials


Other Requirements:


  • This position may require some work on weekends and holidays.



  Omeros is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to status as a protected veteran or a qualified individual with a disability, or other protected status such as race, religion, color, national origin, sex, age, marital status, or any other factor determined to be unlawful by federal, state, or local statutes.

It is our policy to provide reasonable accommodation to anyone with a disability who needs assistance completing the job application process. If you need assistance, you can either send an e-mail to hr@omeros.com or contact Omeros, asking for Human Resources, at (206) 676-5000.




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